I have always had multiple programs,it's really not that hard to promote and keep track of if your organized.You can use simple rotators with traffic exchanges and i found that at least once a week i visit and log into each program and check out everything including messages and new referrals.It's really all got to do with how much time you have...Some programs are complicated and need to be worked alone...I try and stay with simple but powerful and well paying programs that do not require twisting someone's arm to join...most programs handle the sales for you,all you need to do is advertise the link and get the referral....Best Easy Work is a great example,they are awesome at closing the deal...Prosperity marketing System is another no brainer....Easy1up is simple yet very profitable...I'm sure everyone has a favorite and that's what makes this business great...find something you like and stick with it.